Rubbing Alcohol vs. Hydrogen Peroxide for Disinfecting (2024)

Rubbing alcohol and hydrogen peroxide are two common household cleaners. Chances are, you’ve probably come into contact with one or both of these chemical compounds at some point.

One isn’t necessarily more effective than the other. With that said, their effectiveness can vary depending on how you use them and the types of germs you’re trying to kill.

Let’s take a closer look at the key differences between rubbing alcohol and hydrogen peroxide, as well as how to use them effectively.

About rubbing alcohol

The active ingredient in rubbing alcohol is isopropanol, also known as isopropyl alcohol. A bottle of rubbing alcohol typically contains between 60 to 80 percent isopropanol dissolved in water.

Rubbing alcohol has many uses. It’s a powerful germicide, which means it has the ability to kill a wide variety of germs, including bacteria, viruses, and fungi. Rubbing alcohol is used in healthcare settings to disinfect hands and surfaces, but can also be used as a household cleaner.

In concentrations of 70 percent or higher, isopropanol has the ability to kill the new coronavirus that causes COVID-19.

About hydrogen peroxide

Unlike isopropanol, hydrogen peroxide is not a type of alcohol. You might recognize its chemical formula, H2O2, as being similar to that of water (H2O). The difference is that hydrogen peroxide has two oxygen atoms instead of one. That one extra oxygen atom makes it a strong oxidizer.

When you buy hydrogen peroxide from a pharmacy, you’re getting a solution that contains 3 percent hydrogen peroxide dissolved in water. This formulation is strong enough to kill harmful microorganisms, including bacteria, viruses, fungi, and spores.

Like rubbing alcohol, it also has the ability to destroy SARS-CoV-2, the new coronavirus. Additionally, hydrogen peroxide has many other uses in the home.

While hydrogen peroxide makes a great disinfectant, it’s not gentle enough to be used on your skin. That’s why you won’t find it in hand sanitizer.

There’s no definitive answer as to which is better at killing germs. The effectiveness of rubbing alcohol and hydrogen peroxide varies according to:

  • the surface you’re cleaning
  • the type of germs you want to destroy
  • how quickly you want it to work

Disinfecting your skin, surfaces, and fabric

In general, rubbing alcohol is a better option for your skin. This isn’t necessarily because it’s more effective, but because hydrogen peroxide is too harsh to be used on your skin.

Both can be used effectively on hard surfaces such as doorknobs, countertops, porcelain, stainless steel, and glass. However, repeated use of either substance can affect the finish of these surfaces. It’s a good idea to check whether it’s safe to use the product before you apply it.

Rubbing alcohol can also be used to disinfect some fabrics, but you’ll want to avoid using it on anything that’s synthetic or delicate. Using hydrogen peroxide on fabrics can cause yellowing.

The germs they kill

Both rubbing alcohol and hydrogen peroxide have the ability to kill many types of bacteria, including:

  • Acinetobacter baumannii: can cause infections in your blood, urinary tract, and lungs
  • E. coli: can lead to intestinal infection and sickness
  • Enterococcus faecalis: can lead to infections in your blood, heart lining, brain and spinal cord, urinary tract, gums, and open wounds
  • Listeria monocytogenes: usually found in contaminated foods, a listeria infection usually causes mild symptoms, but can lead to bacterial meningitis, endocarditis, and sepsis in some people
  • Pseudomonas aeruginosa: can cause many types of infections in people with weakened immune systems
  • Salmonella: a common cause of food poisoning, this bacteria affects the small intestines
  • Staphylococcus aureus: can cause food poisoning

According to a 2010 study, rubbing alcohol doesn’t eliminate C. difficile spores.

Rubbing alcohol and hydrogen peroxide are also effective at disabling many enveloped viruses, which have a fatty outer membrane. These include:

According to the Centers for Disease Control and Prevention (CDC), isopropanol is less effective at killing nonenveloped viruses such as hepatitis A and rotavirus. Hydrogen peroxide is also ineffective against the hepatitis A virus.

Hydrogen peroxide is reported to be most effective when it’s allowed to sit on surfaces for at least 10 minutes at room temperature. If time is of the essence, rubbing alcohol may be a better option for disinfecting surfaces.

  1. Be sure to use a rubbing alcohol product that contains at least 70 percent isopropanol. Don’t dilute rubbing alcohol with water.
  2. First, wash the surface you wish to disinfect with soap and water.
  3. Then use a wipe, towel, or spray bottle to evenly apply the rubbing alcohol to the surface.
  4. Let it sit for at least 30 seconds.

  1. Solutions of at least 3 percent hydrogen peroxide make efficient household disinfectants. Don’t dilute.
  2. As with rubbing alcohol, first wipe down the surface with soap and water.
  3. Use a spray bottle or a clean rag to apply the hydrogen peroxide to the surface.
  4. Allow the solution to sit on the surface for at least 10 minutes. You don’t need to wipe it off.

Both rubbing alcohol and hydrogen peroxide were once commonly used to clean minor wounds such as cuts and scrapes.

This is no longer recommended. While rubbing alcohol and hydrogen peroxide will kill harmful bacteria, they can be too harsh on the tissue surrounding the wound. Applying one of these substances may even make it harder for the wound to heal.

Instead, thoroughly rinse a superficial wound with running water to remove any dirt and debris. Then gently clean around the edges of the wound with mild soap to disinfect the area.

  • Don’t ingest either rubbing alcohol or hydrogen peroxide. They’re meant for external use only.
  • Avoid getting either substance in your eyes.
  • Make sure any indoor area is well ventilated when using either product.
  • Try to avoid getting hydrogen peroxide on your hands and skin, as it can cause irritation.
  • Store both products in a cool, dry place that’s out of reach of children and pets.
  • Rubbing alcohol is flammable and should be kept away from flames.
  • Both products can expire. Once expired, they might not be able to kill germs as effectively. Always check the expiration date on the product label before using.

Rubbing alcohol and hydrogen peroxide both kill most bacteria, viruses, and fungi. In general, rubbing alcohol is better at killing germs on your hands, as it’s gentler on your skin than hydrogen peroxide.

Hydrogen peroxide is most effective when it’s allowed to sit on surfaces for at least 10 minutes at room temperature. Rubbing alcohol has the ability to kill pathogens on your skin and surfaces in less time.

When sanitizing with either product, always carefully follow the instructions on the product label.

Rubbing Alcohol vs. Hydrogen Peroxide for Disinfecting (2024)

FAQs

Rubbing Alcohol vs. Hydrogen Peroxide for Disinfecting? ›

Rubbing alcohol can kill them within 10 seconds. Hydrogen peroxide is another antiseptic, or disinfectant, that kills viruses and various forms of bacteria. But it needs more time than rubbing alcohol does to kill germs. It needs up to 5 minutes to do its job.

Is hydrogen peroxide or rubbing alcohol better for disinfecting? ›

The bottom line. Rubbing alcohol and hydrogen peroxide both kill most bacteria, viruses, and fungi. In general, rubbing alcohol is better at killing germs on your hands, as it's gentler on your skin than hydrogen peroxide.

Does hydrogen peroxide sanitize or disinfect? ›

Hydrogen peroxide is recognized by the Centers for Disease Control and Prevention (CDC) as a “stable and effective disinfectant when used on inanimate surfaces.” According to the CDC, hydrogen peroxide can be used against a number of bacteria, viruses, fungi, spores, and yeast.

Can you use hydrogen peroxide as a disinfectant cleaner? ›

Hydrogen peroxide is incredibly effective; it cleans, disinfects, and deodorizes surfaces. It is also anti-bacterial, anti-fungal, anti-mold, and anti-mildew. This is especially useful in healthcare facilities fighting against infections and other emerging threats.

How effective is rubbing alcohol as a disinfectant? ›

70% isopropyl alcohol kills organisms by denaturing their proteins and dissolving their lipids and is effective against most bacteria, fungi and many viruses, but is ineffective against bacterial spores (CDC, 2020).

What are the disadvantages of hydrogen peroxide as a disinfectant? ›

Hydrogen peroxide disinfection requires a high dose. The main disadvantage is the small disinfecting and oxidising ability of hydrogen peroxide at active concentrations (tens of milligrams per litre), which are required for swimming pool disinfection.

Which is a better disinfectant vinegar or hydrogen peroxide? ›

Hydrogen peroxide is a disinfectant that kills germs and viruses safely and quickly without using potentially toxic chemicals. This makes it a great disinfectant. In addition, its antibacterial and antiviral qualities are more effective than distilled white vinegar and rubbing alcohol.

Can hydrogen peroxide help with Covid 19 disinfection? ›

Disinfectants like hydrogen peroxide or bleach are important to kill coronavirus on household surfaces, but they must be used safely to avoid harming health and making asthma worse. When is disinfection needed? All households can consider routine disinfection of “high- touch” surfaces (like doorknobs).

Do you need to rinse off hydrogen peroxide? ›

No, you don't need to rinse it off after using it to disinfect. However, you can rinse it off if you want to. Uses for hydrogen peroxide cleaning vary, and you'll want to rinse some things like fabrics and children's toys.

Why 70% isopropyl alcohol is a better disinfectant? ›

70% IPA solutions penetrate the cell wall more completely which permeates the entire cell, coagulates all proteins, and therefore the microorganism dies. Extra water content slows evaporation, therefore increasing surface contact time and enhancing effectiveness.

What concentration of alcohol is most effective as a disinfectant Why? ›

Ethyl alcohol, at concentrations of 60%–80%, is a potent virucidal agent inactivating all of the lipophilic viruses (e.g., herpes, vaccinia, and influenza virus) and many hydrophilic viruses (e.g., adenovirus, enterovirus, rhinovirus, and rotaviruses but not hepatitis A virus (HAV) 58 or poliovirus) 49.

Why 70% alcohol is better disinfectant than 100% alcohol? ›

You can buy rubbing alcohol with a concentration of 70% or 99% isopropyl alcohol. Even though you may think the higher concentration is more effective, experts say 70% is actually better for disinfecting. It has more water, which helps it to dissolve more slowly, penetrate cells, and kill bacteria.

How to make homemade disinfectant spray with hydrogen peroxide? ›

Ingredients:
  1. 12 ounces alcohol (95%) (preferably ethanol but can use other alcohol)
  2. 3 ½ ounces distilled water.
  3. ½ teaspoon hydrogen peroxide.
  4. 30-45 drops essential oil as desired (optional. For scent and antiviral and cleaning properties)

How do you disinfect your house with hydrogen peroxide? ›

Pour the hydrogen peroxide into the spray bottle. Spray down the hard surfaces in your bathroom, kitchen, living room and bedrooms you are trying to disinfect (tubs/showers, trashcans, doorknobs, toilets, sinks, etc.). Allow the solution to bubble on the surface for 5 or so minutes. Wipe off.

Is hydrogen peroxide a good cleaning solution? ›

According to the CDC , hydrogen peroxide is effective at removing microorganisms, including bacteria, yeasts, fungi, viruses, and spores, making it a good choice for cleaning your bathroom.

Is hydrogen peroxide a good disinfectant for wounds? ›

Hydrogen peroxide used to be a popular antiseptic for cleaning wounds and treating acne. But it's not a good idea to use it for those purposes, since it can irritate your skin. If you don't want to throw away your brown bottles, you can use hydrogen peroxide to clean and disinfect around the house.

Is hydrogen peroxide the same as rubbing alcohol for removing stains? ›

Rubbing alcohol gets out ink stains from clothes and walls. Hydrogen Peroxide gets out fresh blood stains quickly and economically.

Does rubbing alcohol disinfect as well as bleach? ›

Using alcohol as a prolonged disinfectant can cause hardening and cracking of skin, rubber, and some plastics. If used to sanitize personal items, it can also cause discoloration after repeated uses. Bleach is a strong and effective disinfectant as well as a great alternative if you can't get your hands on alcohol.

Can you use rubbing alcohol and hydrogen peroxide together? ›

From a chemical perspective, mixing hydrogen peroxide solution and rubbing alcohol/isopropyl alcohol is safe. They won't react together without the right catalyst. To minimise the possibility of a reaction, it would be best to mix them together just before use.

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